Victoria’s road toll stands at 121 – 17 higher than the same point last year – after three deaths on the state’s roads on Tuesday.

The Calder Freeway has re-opened following the horror fuel tanker crash that claimed the life of one man, while two men have been killed and a third is fighting for life after their car crossed onto the wrong side of the road at Kallista.

The car crashed head-on with a four-wheel-drive on Monbulk Road just after 8pm.

The driver of the four wheel drive was not injured.