Emergency services are at the scene of a fatal crash in Flora Hill, near Bendigo.

Police say the white sedan hit a stationary truck about 1.30am.

The female passenger died at the scene while the male driver was taken to hospital with serious injuries.

Two men in the truck were also taken to hospital with minor injuries.

Meanwhile, a car has crashed into a home at Sydenham this morning.

Police say the car crashed into a parked car on Bhangoo court about 1am.

It pushed the vehicle up the driveway, through windows and into the front living room.

The driver and the single person home at the time were not hurt.

They are being questioned by officers.