Three men have been seriously injured following a crash in Kealba.

A car crashed into a pole on Sunshine Avenue about 12.45pm.

A man in his 20s and a man in his 30s have been taken to the Royal Melbourne Hospital in critical conditions with upper and lower body injuries.

Another man, aged in his 30s, has been taken to The Alfred Hospital with serious upper body injuries.

The cause of the crash remains under investigation.

Any witnesses or anyone with dash cam or CCTV is urged to contact Crime Stoppers on 1800 333 000 or submit a confidential report online at crimestoppersvic.com.au

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